Phosphatidic Acid and Cardiolipin Coordinate Mitochondrial Dynamics
نویسندگان
چکیده
منابع مشابه
Cardiolipin-mediated mitochondrial dynamics and stress response in Arabidopsis.
Mitochondria are essential and dynamic organelles in eukaryotes. Cardiolipin (CL) is a key phospholipid in mitochondrial membranes, playing important roles in maintaining the functional integrity and dynamics of mitochondria in animals and yeasts. However, CL's role in plants is just beginning to be elucidated. In this study, we used Arabidopsis thaliana to examine the subcellular distribution ...
متن کاملCardiolipin-Mediated Mitochondrial Dynamics and Stress Response in ArabidopsisC
Ronghui Pan,a,b A. Daniel Jones,b,c and Jianping Hua,d,1 aMichigan State University–Department of Energy Plant Research Laboratory, Michigan State University, East Lansing, Michigan 48824 bDepartment of Biochemistry and Molecular Biology, Michigan State University, East Lansing, Michigan 48824 cDepartment of Chemistry, Michigan State University, East Lansing, Michigan 48824 d Plant Biology Depa...
متن کاملPhosphatidic acid and N-acylphosphatidylethanolamine form membrane domains in Escherichia coli mutant lacking cardiolipin and phosphatidylglycerol.
The pgsA null Escherichia coli strain, UE54, lacks the major anionic phospholipids phosphatidylglycerol and cardiolipin. Despite these alterations the strain exhibits relatively normal cell division. Analysis of the UE54 phospholipids using negativeion electrospray ionization mass spectrometry resulted in identification of a new anionic phospholipid, N-acylphosphatidylethanolamine. Staining wit...
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Phosphatidic acid or 1,2-diacyl-sn-glycero-3-phosphate is not an abundant lipid constituent of any living organism to my knowledge, but it is extremely important as an intermediate in the biosynthesis of triacylglycerols and phospholipids and as a signalling molecule. Indeed, it is often over-estimated in tissues as it can arise by inadvertent enzymatic hydrolysis during inappropriate storage o...
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UNLABELLED The accumulation of extracellular amyloid-beta (Aβ) peptide and intracellular neurofibrillary tangles in the brain are two major neuropathological hallmarks of Alzheimer's disease (AD). It is thought that an equilibrium exists between Aβ in the brain and in the peripheral blood and thus, it was hypothesized that shifting this equilibrium towards the blood by enhancing peripheral clea...
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ژورنال
عنوان ژورنال: Trends in Cell Biology
سال: 2018
ISSN: 0962-8924
DOI: 10.1016/j.tcb.2017.08.011